Lithium Orotate (C5H3LiN2O4) is a salt of orotic acid and lithium. It is available as the monohydrate, LiC5H3N2O4·H2O.[1] In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium ions. It is marketed as a dietary supplement.
Lithium orotate is capable of providing lithium to the body, like other lithium salts.
Product Name
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Lithium Orotate
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CAS No
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5266-20-6
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Grade
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Food Grade
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Spec./Purity
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99%
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Appearance
|
White powder
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Shelf Life
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2 years
|
MOQ
|
1kg
|
Storage
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Cool and Dry Place
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Lithium orotate is a dietary supplement that can be used in small doses to treat conditions like manic depression, alcoholism, ADHD and ADD, depression, aggression, PTSD, Alzheimer's Disease and overall stress management.
Lithium orotate has also been used with success in alleviating the pain from migraine and cluster headaches, low white blood cell counts, juvenile convulsive disease, alcoholism and liver disorders. And it is also reported that patients with myopia (nearsightedness) and glaucoma often benefit from the slight dehydrating effect of lithium on the eye, resulting in improvement in vision and reduction of intraocular pressure.
The lithium salt of orotic acid (lithium orotate) improves the specific effects of lithium many-fold by increasing lithium bio-utilization. The orotates transport the lithium to the membranes of mitochondria, lysosomes and the glia cells. Lithium orotate stabilizes the lysosomal membranes and prevents the enzyme reactions that are responsible for the sodium depletion and dehydration effects of other lithium salts.
Because of the superior bioavailability of lithium orotate, the therapeutic dosage is much less than prescription forms of lithium. For example, in cases of severe depression, the therapeutic dosage of lithium orotate is 150 mg/day. This is compared to 900-1800 mg of the prescription forms. In this dosage range of lithium orotate, there are no adverse lithium side reactions and no need for monitoring blood serum measurements.
Identification
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Specification
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Result
|
Appearance
|
White crystalline powder
|
Complies
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Odor
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characteristic
|
Complies
|
Particle size
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100% through 80 mesh
|
Complies
|
Loss on Drying
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≤5.0%
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1.45%
|
Melting Point
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130~142℃
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Complies
|
Stigmasterol
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≥15.0%
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23.6%
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Brassicasterol
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≤5.0%
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0.8%
|
Campesterol
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≥20.0%
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23.1%
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β—sitosterol
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≥40.0%
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41.4%
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Other sterol
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≤3.0%
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0.71%
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Total Sterols Assay
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≥90%
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90.06%(GC)
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Pb
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≤10ppm
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Complies
|
Microbiological Data
|
||
Total Aerobic Count
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≤10000cfu/g
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Complies
|
Yeast & Mold
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≤1000cfu/g
|
Complies
|
E.Coli
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Negative
|
Complies
|
Salmonella
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Negative
|
Complies
|
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