S-Adenosyl-L-methionine (also called S-adenosyl methionine, S-adenosylmethionine, SAMe, or SAM-e in the United States or ademetionine in Europe, and also often abbreviated as SAM and AdoMet)
S-Adenosyl-L-methionine Disulfate Tosylate(SAMe) is synthesized catalyzed by adenosine triphosphate and methionine. Due to its methyl transfer, sulfhydryl transfer and aminopropylation, it participates in a variety of metabolic reactions in the organism, such as the synthesis of nucleic acids, proteins, lipids and secondary metabolites. In addition, it is also a biologically active precursor of coenzyme A and glutathione.
S-Adenosyl-L-methionine (SAMe) is a naturally occurring compound found in every living organism. It plays many important roles in the body, including acting as a methyl donor in a wide range of biochemical reactions. SAMe has been studied for its potential therapeutic use in treating depression, osteoarthritis, and liver disease, among other conditions. It is available as a dietary supplement in some countries.
S-Adenosyl-L-methionine (SAMe) is a coenzyme involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAMe. Although these anabolic reactions occur throughout the body, most SAMe is produced and consumed in the liver.
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Product name | S-Adenosyl-L-methionine Disulfate Tosylate |
CAS No. | 97540-22-2/29908-03-0 |
Appearance | White or almost white powder |
Purity ( HPLC ) | 98.0% to105.0% |
Heavy metals | Not more than 10 ppm |
Loss on drying | Not more than 1% |
Shelf life | 24 months |
Packing | 25kg/drum or customized |
Storage condition | Store in cool place and keep container away from sunlight |
1> S-Adenosyl-L-Methionine can be added in health care supplements.
2> S-Adenosyl-L-Methionine as a dietary supplement.
S-Adenosyl-L-Methionine (SAMe) has been used for a variety of health purposes, including:
It's important to note, however, that more research is needed to fully understand the potential benefits and risks of SAMe supplementation. It's also important to talk to your healthcare provider before starting any new supplement or medication.
1.S-Adenosyl-L-Methionine SAMe is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;
2.S-Adenosyl-L-Methionine SAMe has remarkable preventive effects on chronic active hepatitis, and other factors caused liver injury,heart disease, cancer and so on.
3.S-Adenosyl-L-Methionine SAMe has been found to be as effective as pharmaceutical treatments for arthritis and major depression as well.
Items | Specification | Results |
Total content | ≥98% | 99.1% |
Ademetionine | 50.0~53.0% | 51.8% |
Chemical Reaction | Positive | Positive |
IR | Conforms | Conforms |
Retention time of a major peak | Meet the requirements | Conforms |
Acid value | 1.5~2.5 | 2.1 |
Sadenosyl-L-Homocystein (HPLC) | ≤0.5 | Conforms |
Methithioadenosine(HPLC) | ≤1.0% | Conforms |
Adenine(HPLC) | ≤0.5% | Conforms |
S.S isomer(HPLC) | ≥62.0% | Conforms |
Butanedisufoinc acid | 46.0~49.0% | 47.5% |
Endotoxin | ≤0.3EU/mg | Conforms |
Water content | ≤3.0% | Conforms |
Residue on ignition | ≤0.3% | Conforms |
Heavy metals | ≤10ppm | Conforms |
Conclusion | Conforms with specification |
Q1: Are you a manufacturer or trading company?
A: We are manufacturer, welcome to visit our factory.
Q2: How to confirm the product quality before placing the order?
A:Sample could be provided, and we have the inspection report issued by an authoritative
third-party testing agency.
Q3: What’s your MOQ?
A: It depends on products, different products with different MOQ, we accept sample order or provide free sample for your test.
Q4: How about delivery time/method?
A: We usually ship within 1-3 working days after your payment.
We can ship by door to door courier, by air, by sea, you also can choose your forwarder shipping
agent.
Q5: Do you provide after sales service?
A: TGY provide 24*7 service. We can talk by email, skype, whatsapp, phone or whatever you
feel convenient.
Q6: How to solve the after-sale disputes?
A:We accept Changing or Refunding service if any quality problem.
Q7: What’s your payment methods?
A:Bank transfer ,Western Union, Moneygram, T/T + T/T balance against B/L copy(bulk quantity)
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