Gromwell Root Extract Shikonin is the dry root of Arnebia euchroma or Arnebia mongolica. It mainly contains naphthoquinones, shikonin,shikonin, shikonin and shikonin. It has a long history of medicinal use in China. TCM is mainly used for the treatment of wet macular , purpura, hematuria, drenching and dysentery, heat constipation, burns, eczema, erysipelas, etc. Modern medical research has found that the chemical composition of Arnebia euchroma is complex, with a wide range of pharmacological effects, such as anti-tumor, antibacterial , antiviral, anti HIV, anti fertility, antipyretic, hemostatic, hypoglycemic and so on.

Shikonin, a component of chinese herbal extract, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. Shikoni is a kind of red coloring agent, mainly used in juice drinks, ice cream, popsicles, fruit wine, cheese and spices etc. It can also be used for cosmetics, detergents.

Shikonin prevented the down-regulation of beta-catenin and increased the level of its transcriptional product, cyclin D1, during adipogenesis of 3T3-L1 cells, preadipocytes originally derived from mouse embryo. beta-catenin was a crucial mediator of the anti-adipogenic effects of shikonin, as determined by siRNA-mediated knockdown.

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